How to survive using your keyboard only. Screw that mouse
By pressing ctrl + F2, you open access to your menu bar, which is navigated with arrows, enter, or letters (for a shortcut, type the first letter of the menu item you want to access.
Pressing ctrl + F3 opens up your access to your dock, which can be navigated in the same way as the menu bar.
NOTE: If those actions are not working, then press ctrl + F1 to activate/deactivate this function.
You could really do anything without touching a mouse! So if your mighty mouse runs out of battery and there are no spare batteries…. How convenient!
Don’t forget those simple shortcuts too, like ‘Command () + Shift + A‘ that opens your applications folder (only works when on Finder, Safari for example, gives you autofill preferences…)
Other shortcuts you must know are:
Empty trash: Command () + Shift + Delete
Quit application: Command () + Q
Close current window: Command () + W
UPDATE: oli4 reminded me with his comment; to see a directory of shortcuts, go to System Preferences > Keyboard & Mouse > Keyboard Shortcuts
UPDATE #2: Learned a new shortcut! When on Safari, select a word you don’t know and press ctrl + Command () + D and you will get a quick definition show up as a tool tip kind of thing!

Mind you pimp in Pimp My Mac is not meant to hold that definition
Why don’t you post more shortcuts for others’ convenience in the comments?
Filed under: How To, Leopard, Productivity, Safari, Tips | Tagged: Apple, don't use a mouse, How To, how to's, howto, keyboard, keyboard shortcuts, list of shortcuts, Mac, mouse, Tips, tricks, use keyboard only, use your keyboard only | 5 Comments »