I hate backing things up. You know why? Cause something is just bound to fuck up. While these are my past experiences with .Mac’s BackUp (demo unless you have a .Mac account), I don’t know about other backup applications. However, I found one which seems to get the job done very nicely, and that is iBackup.
Very simple to use, comes with a lot of different plug-ins you can install, and pretty much has any feature that any other back up client comes with, only this one’s free :D. Simple to use, and reliable.
Get iBackup here.